Osage University Partners (OUP), a U.S.-based venture capital firm, has closed Osage University Partners III, L.P. (OUP III) at $273 million.

OUP III marks the firm’s third fund dedicated to investments exclusively in startups that are commercializing university research, bringing OUP’s total assets under management to about $600 million.

The fund will invest in companies developing technology discovered in the laboratories of its partner institutions, as well as in companies across all sectors of life sciences and technology, and across all stages of development, from seed to late stage or pre-IPO.

In 2015, OUP closed its OUP II fund at $215 million, which backed several university spinouts that have gone public.